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“We arbitrarily hijacked small groups of neurons in the visual cortex and virtually re-routed their output to make them control a brain-machine interface, or BMI,” said Jose Carmena, senior author of a paper about the development that will appear March 1 in the journal Neuron. “To gain a reward, the rats learned to produce arbitrary patterns of neural activity unrelated to visual input in order to control a BMI, highlighting the power of neuroplasticity and the flexibility of the brain.”

Neuroscientists have demonstrated the astounding flexibility of the brain by training neurons that normally process
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